In 1838 and 1839, as part of Andrew Jackson's Indian removal policy, the Cherokee nation was forced to give up its lands east of the Mississippi River and to migrate to an area in present-day Oklahoma. The Cherokee people called this journey the "Trail of Tears," because of its devastating effects. The migrants faced hunger, disease, and exhaustion on the forced march. Over 4,000 out of 15,000 of the Cherokees died.

This picture, The Trail of Tears, was painted by Robert Lindneux in 1942. It commemorates the suffering of the Cherokee people under forced removal. If any depictions of the "Trail of Tears" were created at the time of the march, they have not survived.